Thursday, October 31, 2019

Biology of food4 Essay Example | Topics and Well Written Essays - 1250 words

Biology of food4 - Essay Example The malting process entails a period of soaking in water for a certain period, allowing the opening of the husk, and releasing of the barley. The malting procedure stops at the point where the seeds begin to recruit enzymes that can break down the starch in the seeds. After draining the soaked seeds, the fermentation process follows, whereby yeast and lactobacilli utilize the sugars in the seed. The fermentation process runs for a period, until the beer is ready. If Mel had left the seeds to germinate fully, the germinating plant would have utilized the foods stored in the grain. Usually, seeds in the store have a reserve of nutrients in the cotyledon. Under the right conditions, germination of the seeds takes place, a process that compels the germinating seedling to use the nutrients (Pratap and Kumar37). During seed maturation, storage or starch in the cotyledon occurs. When seeds absorb water at the onset of germination, a new process of mobilizing the nutrients for use in growth occurs. The availability of certain enzymes breaks down the starch into simple sugars that the seed utilizes in respiration. The respiratory process yields energy and other waste products such as lactic acid. Moreover, synthesis of other essential nutrients such as proteins takes place in the seed. In the process of making wine, the fruit juice used provides the relevant sugars utilized by the microbes involved in the fermentation process. The wine making process is usually different from that of making beer. In making wines, grape juices serve as the source of both macronutrients and micronutrients required by the microbes, while beer making utilizes seeds. A cost/benefit analysis led to this difference. After it became evident that the seeds used in making beer were critical sources of food for animals, it proved rational for grapes serve as food for microbes in the wine making process, preserving the grains for animals (14). This is in conformity with the fact that animals are hi gher than the microbes. Plants usually produce toxins as an essential part of constitutive defense. Genetic mutation is responsible for the conversion of phenolic compounds and alkaloids to the toxins. Although plants produce toxins as a form of defense, they affect the plant’s reproductive system adversely, and the mutated genesare conferred to the next generation. It is likely that the mutated plants have a higher chance of survival because the toxins protect it from attack by herbivores and insects. Usually, plants exposed to attacks by herbivores, and insects causing detriment to the plant motivates the plant to alter its secondary metabolism and produce toxins. A classic example is the milkweed, which underwent mutation to produce cardenolides that serve as toxins to monarchs. Apricots are seeds and play a critical role because they germinate to yield new plants. Apricot seeds require both macro and micronutrients for use in the metabolic processes involved in germinatio n. From eating apricot seeds, humans obtain carbohydrates, amygdalin, protein, sugars and fats (36). Squash blossoms are flowers involved in the sexual reproduction of the plant. By eating these flowers, the body gains calcium, sodium, iron, vitamins, and carbohydrates. in order to play the role sexual reproduction, these flowers require a range of ten aromatic compounds. A slice of turkey denotes a piece of breast meat. It is an essential portion as it provides

Monday, October 28, 2019

Teen Eating Disorders Essay Example for Free

Teen Eating Disorders Essay The teenage community today is based on the views and opinions of society. Though this may seem harmless on the outside, these opinions have become the poison apple of today’s culture, tearing teenagers lives apart. Specifically, teenagers are falling to eating disorders due to the pictures and habits in the everyday community. Large billboards of flawless models, magazines with dieting tips and get-skinny schemes flood the minds of teenage girls and boys, imprinting the thought that they are obligated to look perfect. Eating disorders have very serious health risks, which can be aided by extensive treatment. Specific habits and signs can identify each disorder. The signs of anorexia nervosa and bulimia are vastly different. Girls that suffer from Anorexia tend to be perfectionists who want to control the amount of food consumed, where Bulimics tend to eat large amounts of food and purge the calories consumed. In anorexia, girls will start â€Å"Wearing baggy clothing, or clothing inappropriate for the season (long sleeves on a hot day)† (Is Your Child Showing Signs of an Eating Disorder?, PR Newswire). This is due to their need to hide the extreme amount of weight loss. Bulimics will hide their purges by spending a lot of time in the bathroom and running the water to cover the sound. Girls with these disorders are sneaky and manipulative. They will go great lengths to hide what they are doing. Although the person that is affected will be in denial these signs are easy to spot and more noticeable then they think. Some times these signs are what can save a persons life. Anorexia Nervosa and Bulimia are detrimental to the human body. Anorexia can lead to dizzy spells, irregular menstrual cycles, hair loss and breakage and eventually death. Bulimia can lead to damaged teeth, rips in esophagus, sores in the mouth and eventually death as well. The health risks are beyond physical but mental as well. Girls with eating disorders almost always have another psychiatric disorder. Some can suffer from depression and anxiety. Eating disorders are often classified as a â€Å"Dual Diagnosis†. With the correct treatment, both disorders can be reversed. It is important for the patient to recognize their symptoms and realize that they are not alone in their situation. Parental support is normally the most important factor in recovery â€Å"The most important thing a parent can do is listen, says Susan McClanahan, Ph.D., a clinical psychologist who specializes in the treatment of anorexia and bulimia.† Treatment is the best answer and is an important step to recovery. Recovery is a slow process that needs a lot of understanding and patience. If the treatment is rushed the patient is more likely to fall back into old habits and relapse. These disorders should been taken seriously watched for in girls of all ages. The ages of teenagers affected by the disorders varies greatly. â€Å"In the United States, as many as 10 in 100 young women suffer from an eating disorder.† (The American Academy of Child and Adolescent Psychiatry.) Due to societies pressure for perfection, the battle with each disorder is in many cases deadly. With the right treatment, severe health risks can be reversed and the disorder will begin to fade, as the signs of a healthy individual will shine through. PR Newswire (2012). Is Your Child Showing Signs of an Eating Disorder? Journal of Business and Economics. http://aacap.org/page.ww?name=Teenagers+with+Eating+Disorders §ion=Facts+for+Families

Saturday, October 26, 2019

Investigation: Water Scarcity in Australia

Investigation: Water Scarcity in Australia Students Name: James Yu Abstract This paper indicates the water scarcity and water pollution in Australia. These two things can be serious problems in Australia because it is so major a food exporting country. The sources we use as references are all websites and two scientific paper. The solution for these two water issues are cloud seeding and enacting some laws which forbid people from throwing plastic casually. However, just clouding seeding probably can work efficiently if Australia have sufficient capital to conduct these experiments. The limitation of this paper is source availability, all what I can use is Internet because it is tough for me to find books on this topic in English version. 1.0 Introduction This scientific paper indicated several causes of water scarcity and water pollution in Australia, and also provided some solutions of solving this issue. Australia is one of the most developed countries all over the world, however, this country got a severe water restriction. One of the most underlying causes is sea surface temperature (SST). In the south of Australia , the SST is lower than average. This signified that there was few evaporation of water, caused atomospheric desiccation, and led to limitation of raining (Sea Surface Temperature (SST) Contour Charts 2013). The cause of water pollution in Australia was polyolefins, which accounts for 52% of plastic production and were used for manufacturing throwaway packaging (Schneider J 2013). These plastics could spoil our food web and ecosystem. Australia mostly gather water from raining and a large proportions of water was used for agriculture, because Australia was a major food exporting country (M. Ejaz Qureshi, Munir A. Hanjr a, Ward J 2013). Our hypothesis was Australia could conquer water scarcity and water pollutionif they develop cloud seeding and enact some regulations on environmental protection. Table 1: Variability of à ¯Ã‚ ¬Ã¢â‚¬Å¡ow in some of the worlds major rivers compared with a Australian rivers. COUNTRY RIVER RATIO BETWEEN THE MAXIMUM and THE MINIMUM ANNUAL FLOWS Switzerland China Sudan USA South Africa Australia Rhine Yangtze White Nile Potomac Orange Hunter 1.9 2.0 2.4 3.9 16.9 54.3 This table illustrated the Australian river got a very unstable fluctuation between the maximum and the minumum flows, compared to one major river in other countries. Reference: http://www.wentworthgroup.org/docs/Chartres__Williams.pdf 2.0 Methodology The source of this scientific paper was all Internet. I typed some key words like Water scarcity in Australia. I look through all the web pages and gathered the beneficial information and type them into search box once again. For instance, I found one of the solutions of water scarcity in Australia is Cloud seeding and I typed this term into search box to get further information. I spent about 40 minutes on researching and found 2 websites for each solution. I haved verified all these sources were all written by reputable professors, scientists or publishers by researching these people and publisher to ensure if their dependency is strong enough for my paper. Some of my sources were another scientific paper. 3.0 Findings Two of the most severe fresh water issues in Australia were water scarcity and water pollution, these problems have existed for last of a decade. These two water issues could be a massive problem for Australia. Cloud seeding was a significant solution which throws drikold into cloud, it could increase supply moderately in Australia. Figure 1 demonstrated the mean of precipitation of seeded clouds was 2X103 m3 exceeded from unseeded clouds, it means seeded clounds can actually raise the percipitation (E. J. Smith). In fact, a great percents of water in Australia was polluted by plastics. Meanwhile, Australian plastic production had increased from 170 thousand in 1950s to 280 million in 2011. Figure 2 shows the distribution of plastic pollution in water of Australian city . Most heavy polluted cities were concentrated in the south-eastern and north-western Australia, the place where need to control the plastic production. Some cities in south-eastern Australia had over 15500 km-2 of pl astic concentrations. During the a long term of flowing, these plastics could be broken down into small fragments within 5 mm length, which commonly called microplastic and damaged to the food web and ecosystem easily. Therefore, we had two methods to solve this issue. Approximately 37% of plastics were used for manufacturing disposable packaging, comprising bottle, cups and bags,hence, the first solution was reducing the production of single-use plastic package and decreased the demand of using these plastic manutacture by advocating awareness of this water issue (Schneider J 2013). Another efficient solution was enact the laws which prohibit people and also factories from dumping plastics into sea. Figure 1: Total rainfall from isolated cumulus clouds The total rainfall of seeded cloud and unseeded cloud whose tops were -100C or cooler with 30 minutes of seeding from isolated cumulus clouds. Reference: http://www.wentworthgroup.org/docs/Chartres__Williams.pdf Figure 2: Distribution map of plastic concentrations in Australia    Marine plastic concentrations in waters around Australia. White crosses indicate location of major Australian cities Reference: http://theconversation.com/australian-waters-polluted-by-harmful-tiny-plastics-20790 4.0 Discussion From the scientists and researchers perspectives, they think that the best solution that is able to augment the amout of water is cloud seeding. Via this solution, Australia could have sufficient supply and overcame water scarcity lightly. But on the contrary, cloud seeding can be very costly. In most of the cases, it takes millions of RMB to implement one cloud seeding, therefore, Australia would better have a strong economic background beforehand like developing their agriculture or IT industry. On the other hand, as for the water pollution in Australia, most of water is polluted by fragmented plastic and majority of people and factories concentrated in the eastern coast of the Australia, so we could see eastern Australia is more polluted than any other part of Australia. Moreover, because it is hardly to eliminate all these plastic pollutants and made sure there is no plastic contamination in the furture in a scientific way, we could just do it in a political approach. For instanc e, government could enact laws of environmental protection or making some advertisments to persuade people do not throw plasctic bags or products into any kind of natural water source. In addition, some eco-friendly organizations can just simply set some dustbins around those highly polluted cities for recycling the plastic. But its a little bit tough for them to conquer water pollution via this method. All in all, I think Australia can conquer these two water issues based on the previous contents. 5.0 Conclusions and Recommendations In general, cloud seeding still got a substaintia chance to resolve water restriction by it extra precipitation. Australia just need to develop their economy and have enough capital to conduct these experiments. To handle the increasing plastic pollution in Australian water, government have appeal people do not throw any plastic manufactures casually and set several laws to forbid people from doing this, in particular the eastern part of Australia. The effectiveness of this measure rely on the governmental actions and Australian qualities. There are some limitations in this scientific paper, first of all is source restrictions. Sources in this paper are all from Internet. The research suggestion is using books references, because books always much more trustworthy than websites. If we get enough money, we will find a new scientific way to reduce the plastic pollution in Australian water. Reference List      Ã‚   Chartres C., Williams J.(2006), Can Australia Overcome its Water Scarcity Problems, Wentworth Group. [Online]. Available from: http://www.wentworthgroup.org/docs/Chartres__Williams.pdf [Accessed 1 October 2016] (2013),Sea Surface Temperature (SST) Contour Charts, NOAA. [Online]. Available from: http://www.ospo.noaa.gov/Products/ocean/sst/contour/ [Accessed 1 October 2016] (2013), M. Ejaz Qureshi, Munir A. Hanjra, Ward J.,Impact of water scarcity in Australia on global food security in an era of climate change, Science Direct. [Online]. Available from: http://www.sciencedirect.com/science/article/pii/S0306919212001170 [Accessed 1 October 2016] E. J. Smith, Cloud Seeding Experiments in Australia, Berkeley. [Online]. Available from: http://digitalassets.lib.berkeley.edu/math/ucb/text/math_s5_v5_article-10.pdf [Accessed 1 October 2016] Schneider J.(2013), Australian waters polluted by harmful tiny plastics, The Conversation. [Online]. Available from: http://theconversation.com/australian-waters-polluted-by-harmful-tiny-plastics-20790 [Accessed 2 October 2016

Thursday, October 24, 2019

Why John Brown Chose Violence :: essays research papers

Why do you believe that John Brown believed that the situation in the U.S. at the time could only be solved by bloodshed and not compromise?   Ã‚  Ã‚  Ã‚  Ã‚  I believe that there are many reasons why John Brown believed that violence was the only way he could prevail in the fight to end slavery in the United States. First of all; at this time in history, issues were moving fairly quickly. As soon as Kansas was to become a territory, supporters from both the North and South rushed to settle on the land and tried to gain control of the vote in the area. Secondly, it probably seemed that any attempts at compromise at that time had not, and would not, get very far in the issue. Lastly, the most prominent reason I believe that John Brown felt violence was the only answer, was because of his belief in God. As he stated in his speech to the courts during his trial, he felt that what he did was not wrong. Sacrificing his life was worth it; even if it was just one step towards ending slavery, something that was so cruel and wicked anyway, his violence was no worse than the slavery.   Ã‚  Ã‚  Ã‚  Ã‚  When the Kansas-Nebraska Act was introduced in the U.S., the North was upset because the new territories would probably be pro-slavery. As soon as they could, both sides of the issue sent in settlers to try and gain control. This â€Å"race for Kansas† made the race to make a final decision on the issue of slavery in the U.S. an even more urgent issue. This battle to decide what side the two new territories would be on probably pushed the issue so hard it caused a lot of discomfort and probably hurried people like John Brown into making decisions quickly, because people were afraid. I believe that the rush to make a ruling for or against slavery was one reason why John Brown chose bloodshed over compromise.   Ã‚  Ã‚  Ã‚  Ã‚  The second reason I believe Brown picked violence over negotiation was because of the lack of communication. It probably seemed a hopeless endeavor to even try to correspond with the South on the issue, especially after violence had already begun in many places; not to mention in the act of slavery itself. It would have been very hard for either side to civilly speak or negotiate with the opposition in an reasonable manner.

Wednesday, October 23, 2019

An Existentialism View Toward Batman and Naruto Essay

I. Theory of Existentialism Existentialism is a philosophical movement that posits that individuals create the meaning and essence of their lives, as opposed to deities or authoritites creating it for them. It emerged as a movement in twentieth-century literature and philosophy, though it had forerunners in earlier centuries. Existentialism generally postulates that the absence of a transcendent force (such as God) means that the individual is entirely free, and therefore, ultimately responsible. It is up to humans to create an ethos of personal responsibility outside any branded belief system. In existentialism views, personal articulation of being is the olny way to rise above humanity`s absurd condition of much suffering and inevitable death. Existentialism is a reaction against traditional philosophies, such as rationalism and empiricism, that seek to discover an ultimate order in metaphysical principles or in the structure of the observed world, and thereby seek to discover universal meaning. Existentialism originated with the nineteenth-century philosophers Soren Kierkegaard and Friedrich Nietzsche. It became prevalent in Continental philosophy, and literary figures such as Fyodor Dostoevsky also contributed to the movement. In the 1940s and 1950s, French existentialism such as Jean-Paul Satre, Albert Camus, and Simone de Beauvoir, wrote scholarly and fictional works that popularized existential themes such as â€Å"dread, boredom, alienation, the absurd, freedom, commitment, and nothingness. † Walter Kaufmann describes existentialism as â€Å"The refusal to belong to any school of thought, the repudiation of the adequacy of any body of beliefs whatever, and especially of systems, and a marked dissatisfaction with traditional phylosophy as superficial, academic, and remote from life. † Existentialism tends to focus on the question of human existence – the feeling that there is no purpose, indeed nothing, at the core of existence. Finding a way to counter this nothingness, by embracing existence, is the fundamental theme of existentialism, and the root of the phylosophy’s name. In existentialism view, they asserts that a human finds oneself already in a world and prior context that the human cannot think away. In other words, the ultimate and unquestionable reality is not consciousness but existence. A central proposition of existentialism is that humans define their own meaning in life. Such a view might be phrased technically by philosophers as existence precedes essence, that is a human’s existence conceptually precedes the essence or meaning that may be ascribed to the life. Satre, in Essays in Extentialism, further highlights this consciousness of being thrown into existence in the following fashion: â€Å"If man, as the existentialist conceives him, is indefinable, it is because at first he is nothing. Only afterward will he be something, and he himself will have made what he will be. † Emphasizing action, freedom, and decision as fundamental, existentialist oppose themselves to rationalism and positivism. That is, they argue against definitions of human beings as primarily rational. Rather, existentialists look at where people find meaning. Existentialism asserts that people actually make decisions based on what has meaning to them rather that what is rational. A further type of existentialism is agnostic existentialists, who make no claim to know whether or not there is a â€Å"greater picture†; rather, they simply assert that the greatest truth is that which the individual chooses to act upon. II. What is Superhero A superhero – sometimes written as super hero – is a fictional character of extraordinary physical ability dedicated to acts in the sake of public interest. Since the debut of the prototypal superhero Superman in 1938, stories of superheroes – ranging from brief episodic adventures to continuing years-long sagas – have dominated American comic books and crossed over into other media. A female superhero is sometimes called a superheroine or super heroine. By most definitions, characters need not have actual superhuman powers to be deemed superheroes, not, although sometimes terms such as costumed crimefighters are used to refer to those without such powers who have many other common traits of superheroes. The two-word version of the term is a trademark co-owned by DC Comics and Marvel Comics. There have been successful superheroes in other countries most of whom share the conventions of the American model. Examples include Cybersix from Argentina, Captain Canuck from Canada and the heroes of AK Comics from Egypt. For this Western area, I will take Batman as the representative. Unlike many superheroes, Batman has no superpowers and instead relies on his own scientific knowledge, detective skills, an athletic abilities. Batman is physically at the peak of human ability in dozens of areas, notably martial arts, acrobatics, strenght, and escape artistry. Rather than simply outfighting his opponents, Batman often uses cunning and planning to outwit them. Batman’s costumes incorporates the imagery of a bat in order to frighten criminals. Japan is the only country that nears the US in output of superheroes. The earlier of these wore scarves either in addition to or as a substitute for capes and many wear helmets instead of masks. Moonlight Mask, Ultraman, Kamen Rider, Super Sentai (the basis for Power Rangers), Metal Heroes and Kikaider have become popular in Japanese tokusatsu live-action shows, and Science Ninja Team Gatchaman, Casshan, The Guyver, and Sailor Moon are staples of Japanese anime and manga. However, most Japanese superheroes are shorter-lived. While American entertainment companies update and reinvent superheroes, hoping to keep them popular for decades, Japanese companies retire and introduce superheroes more quickly, usually on an annual basis, in order to shorten merchandise lines. In addition, Japanese manga often targets female readers, unlike U. S. comics, and has created such varieties as â€Å"magical girl† (e. g. Cardcaptor Sakura) for this audience. For this Eastern area, I will take Naruto as the representative. Naruto whose full name is Uzumaki Naruto is a young boy who dreams of becoming the leader of his Hidden Village. It will be difficult though for Naruto, because when he was a baby an evil demon was placed inside him to stop its rampage. As Naruto grew the townspeople saw Naruto himself as the demon, even though he was merely its container. Naruto lives in a world populated by ninja villages. The ninja serve as the armies for the countries that inhabit the world. Most of the countries have their own Hidden Village, which serves to train and manage the ninja of the country. Also the ninja in the series are able to utilize jutsu techniques, which are the secrecy, body and illusion arts of the ninja. These allow the ninja to perform many amazing skills such as the manipulation of the surrounding elements. III. Batman and Naruto: Their Differences and Their Revelance In Existentialism The true feature of Batman as a common people is Bruce Wayne, a millionaire industrialist. He inherited a big corporation, Wayne Corporation, from his father. The ego ‘Batman’ was born because of two accident. The first was the murder of Bruce’s parents. Bruce witnessed his parent killed in a gun-accident. A street-criminal shot them to death. The second was Bruce falling down into a cave in Wayne’s manor. He fell into a dark and humid cave where a hundred of bats lived. Those two accidents led Bruce to learn about martial arts and gadget-operating skill in order to fight the crime in Gotham city. His fear of bat made him wear a bat-costume in doing his operation. Thus, Batman as a superhero who fight a crime has born. This is the very purpose why Batman wants to fight crime: a personal vendetta against criminals. Since Batman does not have any superpowers, he relies on his own scientific knowledge, detective skills, an athletic abilities. Also his wealth enables him to get much modern and sophisticated gadget in order to beat his nemesis. In other hand, Naruto, instead of his lack of intellectual ability in solving a problem, his friend still considers some of his actions brilliant. Naruto does all of his action by intuition, not by a precise step as a ninja should do. What makes Naruto a superhero is that he possesses massive abundant chakra energy inside his body. This chakra is originated from a Nine-Tailed Demon Fox that is sealed inside his body. Together with his friends and mentor, Naruto solve the problem and fight with the evil ninjas. They act in a group of 4 ,3 ninjas and a mentor. They perform a close combat by using martial arts and ninjutsu, and a long-range combat by using flying dagger or shuriken. Once they accomplished a mission, they report to the hokage, which is the leader of the village. Yet, the very important thing that makes they both become a superhero is that there exist some nemesis, villains, that must be eliminated. They both make some struggles to get rid of those system distracted. What differentiate them is the way they make these struggles. Batman eliminates crime in Gotham by his own rule. He does not obey the rules prevailed in that city. He intentionally takes action againts criminal without involving the authorities. It can be concluded that Batman makes his own system to fix the system. However, Batman – intentionally or not – does not kill his enemy. He just sents those criminals to the authorities, to be prisoned or not. Batman’s worst nemesis, The Joker, is still alive until now. Although they often have some ‘fight’, but neither Batman or The Joker is condemned to death. While Naruto’s job is to keep the system in his village to be kept save. He does not violate the system prevailed in his village, instead he is forced to obey that system. His acts are being ruled by Hokage, the highest authority in the village. He is a kind of ‘paid’ superhero that acts upon a mission that is given by that Hokage. Once they accomplished that mission, they have report to that Hokage. Here, Naruto biggest enemy, Kabuto, is remain alive until now. What makes this difference? It is because the different culture that affect the people in West and East. Why Batman have a nerve to make his own system to fix the main system prevailed in his city is due to the Western way of thinking. Western culture tends to emphasize critical thinking. They are learned to break the rules if they think that there are some errors in those rules. Their new ideas are being welcomed, even they are supported to make new inventions. While Eastern country tend to ‘close their eyes’. They have to accept what the older people says. They are not being couraged to make some critics toward the culture. They tend to give high respect (sometimes not in a proper measure) toward conventional ideas. Here it implies in the way Batman and Naruto makes their struggle to fight crimes. Then another point where existentialism takes place also emmerges. Why those superheroes do not kill their enemies? It is because they ‘need’ their nemesis so that they can be a superheroes still. Let’s we go back to the question of what makes those superheroes superhero? What do they pursue? They want to eliminate crimes. Then we come to the question of what causes this crime? Criminals. So superheroes exist because there are some criminals. If there are no criminals, so there are no superheroes. Like what Satre has said, â€Å"If man, as the existentialist conceives him, is indefineable, it is because at first he is nothing. Only afterward will he be something, and he himself will have made what he will be. † Thus, superhero is nothing if there is no criminal to make him defineable. This is the meaning of existence preceding essence. I would like to use the term that coined by Heidegger, â€Å"throwness†, that is human beings are â€Å"thrown† into existence without having chosen it. Whether superhero or the enemy do not have the power to choose what they want to be. First they just exist in the world, then they just do the thing that they believe as a greatest truth. This is that greatest truth that they choose to act upon to find the essences of their existencies. Noviana Indah Tri Wahyuni a paper for Comparative Studies Superhero Theme.

Tuesday, October 22, 2019

The Babe of Bethlehem †Theology Essay

The Babe of Bethlehem – Theology Essay Free Online Research Papers This Christmas season, if at all possible, hold a baby in your arms. What do you feel, think, and wonder about that sweet, innocent baby? Perhaps you marvel at the new life in your arms and consider the potential of unique giftedness and blessings wrapped up in such a tiny bundle of life. More that 2,000 years ago the birth of one baby born in the tiny, dusty village of Bethlehem changed the world and divided history into BC and AD. The Babe of Bethlehem became the hinge, the pivotal point on which the destiny of the world turns. dAs the small land of Israel became a crossroad of the world, so the Babe of Bethlehem became the crossroad that determines the direction your life will take. This Christmas it is imperative that you focus on the Babe of Bethlehem. Consider the true Christmas story. (Read Luke 2:1-40.) First consider BETHLEHEMS CENSUS. The Roman Emperor Augustus decreed that all citizens of the Roman Empire must go to their own town to register for the census. Joseph, who was a descendant of King David, had to go to Bethlehem. Bethlehem was King Davids ancestral home. So, Joseph took Mary, his fiancà ©e, who was with child by the Holy Spirit. Augustus had no idea that in the midst of the Roman governmental census, that the Babe of Bethlehem, the one who would hold the governments of the world on His shoulders, would be born. Isaiah prophesied, Listen, will you the royal family of David! The virgin will conceive a child! She will give birth to a son and will call him Immanuel God with us' (Isaiah 7:13 NLT). For a child is born to us, a son is given to us. And the government will rest on his shoulders. These will be his royal title: Wonderful Counselor, Mighty God, Everlasting Father, Prince of Peace (Isaiah 9:6-7 NLT). One day this Babe of Bethlehem will come to rule and reign as King of Kings and Lord of Lords. Presently he rules in the hearts and lives of those who make room for him. Does he rule in your heart? Second BETHLEHEMS CHILD. Nowhere in the New Testament are we actually told to celebrate and commemorate this babes birth. We are told to celebrate and commemorate his death and resurrection. Why is that? Because Christ was born to die as a sacrifice for our sins. Christmas rightly celebrated, helps us remember why this child was born. In Bethlehem there was no room in the inn. So Jesus was born in a stable and laid in a manger (a feed trough for animals). Christ was wrapped in swaddling clothes. Jesus came to die as a sacrificial lamb. (Read Isaiah 53.) He was wrapped in strips of cloth and laid in a tomb. On the third day He arose, proving He is the Christ, the Messiah. Handels Messiah reminds us that Christmas includes the birth, death, and resurrection of Jesus Christ. Bethlehems child must be crowned as king. Consider the manger Jesus was laid in. It reminds us that we must feed on Christ. This child of Bethlehem (Bethlehem means house of bread) announced that He is the Bread of Life. By faith and repentance we spiritually eat of the Christ of Christmas. His torn flesh and spilt blood on the cross is our salvation and daily bread. Third BETHLEHEMS CELEBRATION. The night Christ was born an angel appeared to shepherds out in the field guarding their sheep. They announced the good news, Dont be afraid! I bring you good news of great joy for everyone! The Savior yes, the Messiah, the Lord has been born tonight in Bethlehem. Suddenly the angel was joined by a vast host of others the armies of heaven praising God. Glory to God in the highest heaven and peace on earth to all whom God favors' (Luke 2:8-20 NLT). For all those who receive Christ into their heart as Savior and Lord, there is a joyful celebration. Isaiah prophesied of this day, In that day you will sing . . . with joy will you drink deeply from the fountain of salvation! In that wonderful day you will sing (Isaiah 12 NLT). When the shepherds saw the Babe of Bethlehem, they went back to their flocks glorying and praising God. When you really see the Babe of Bethlehem and receive him as your Savior, you will sing a new song and celebrate with joy, in worship of Christ the Lord. Christmas brings the joy of Christ. Today you can receive the new life that the Babe of Bethlehem came to give you. A Admit you have sinned. For all have sinned and fall short of the glory of God. (Romans 3:23) B Believe in Jesus. For God so loved the world that he gave his one and only Son, that whoever believes in him shall not perish but have eternal life. (John 3:16) C Confess and leave your sin. If we confess our sins, he is faithful and just and will forgive us our sins and purify us from all unrighteousness. (1 John 1:9) Research Papers on The Babe of Bethlehem - Theology EssayPersonal Experience with Teen PregnancyThe Masque of the Red Death Room meaningsComparison: Letter from Birmingham and CritoCanaanite Influence on the Early Israelite ReligionBringing Democracy to AfricaTwilight of the UAWHarry Potter and the Deathly Hallows EssayBook Review on The Autobiography of Malcolm XNever Been Kicked Out of a Place This NiceLifes What Ifs

Monday, October 21, 2019

Celebrating Presidents Day for Micigan Veterans

Celebrating Presidents Day for Micigan Veterans TWO REASONS TO CELEBRATE PRESIDENTS’ DAY FOR MICHIGAN VETERANS The third Monday of February marks Presidents’ Day. It is a federal holiday and, in Michigan, a state holiday as well.Do you know why we celebrate Presidents’ Day? We suggest that you check out this interesting article by USA Today. As the article notes, the answer to that question is actually the subject of some debate.Some people believe that we should use Presidents’ Day to honor two of our most noteworthy presidents – George Washington and Abraham Lincoln. However, others consider it to be a day to honor all of our presidents.We won’t attempt to settle that debate here.However, as a law firm that works with veterans throughout Michigan, we want to share more about these two important reasons to celebrate on February 20th:Many American presidents served in battle.Many veterans who file for disability benefits through the Department of Veterans Affairs served in military operations in Iraq, Afghanistan, Vietnam, Bosnia, Korea and other regions. Th ey should know that many of our nation’s presidents served our country in combat as well.It starts with our very first president, Washington, who served as the commander of the Continental Army in the American Revolutionary War. More recently, our 41st president, George H.W. Bush, fought in the Pacific as a U.S. Navy pilot during World War II.We should also point out that that many people who were candidates for president served in combat as well. Sen. John McCain (R-Arizona) readily comes to mind. You should read his gripping first-person account of his experience as a prisoner of war for five years in North Vietnam.As ABC News reports, to this day, McCain cannot â€Å"raise his arms high enough to comb his hair† and tries to avoid â€Å"repetitive exercise involving his arms† due to the injuries he suffered during his service.A total of 31 presidents served in the military.Out of 45 presidents, a total of 31 served in the military, as the USO notes. The Vetera ns Health Administration provides a complete list of those presidents, including the highest rank they held while in service.The majority of presidents served in the Army or as militia members. However, since the mid-20th century, the U.S. Navy or Naval Reserve produced the most veterans sworn into office.Of course, military service is not required to enter the Oval Office. However, the traits that military life instills – honor, courage and leadership – clearly prepare a person to become the leader of our country.When you celebrate Presidents’ Day as a veteran, you are actually celebrating many of your fellow veterans and honoring all that they have gone through and lost in exchange for our freedoms. The Disability Attorneys of Michigan hope you enjoy the holiday and take a break from your schedule to enjoy time with family and friends.If you need assistance with your VA disability benefits claim, please feel free to contact us to discuss your case. We focus sp ecifically in the area of disability benefits claims and consider it to be an honor to work with so many clients who served our country.

Sunday, October 20, 2019

Essay Assignment

Essay Assignment Essay Assignment Essay Assignment: A Plan of Actions Essay assignment is not difficult at all, if you have a definite plan of actions, of course. You see all the essays are similar to each other as they have their own definite structure; if you follow this very structure you will never be in trouble with your essay assignment writing. Essay Assignment Writing Steps Thus, this is essay structure and a brief plan of what you have to do if you want to succeed in your essay assignment writing: Choose a topic for your essay assignment writing; at this point, it is recommended to choose a topic, which it will be rather interesting for you to deal with, or otherwise, it will not be simple and interesting for you to be engaged into the process of your essay assignment completing. Try to find as much literature devoted to the topic of your essay assignment, as it is possible in order you could present full information related to the topic of your essay assignment. After you have researched the topic of your essay assignment, think which findings you have made and try to stay concentrated on them during the process of your essay assignments writing: Remember that your essay assignment should consist of the following parts: an introduction where you present the topic and the aim of your essay assignment along side with the thesis that is considered to be the main point of your essay assignment; the body where you have either to prove or disapprove the thesis you have presented in the introductory part; the conclusion, where you have to restate your thesis one more time and to prove its relevance with the help of the findings you have made in the body. After your essay assignment is ready, we recommend you to proofread it and edit it in order to make it free from grammar mistakes, which greatly influence your grade for the whole essay assignment writing. If you have an opportunity to give your essay assignment to be proofread by the professionals, who work for the assignment writing services, do it, as this very proofreading really guarantees that you are going to get the highest grade for your essay assignment writing. Essay Assignment: Concluding Note This is an approximate plan of your actions you have to make in order to succeed in essay assignment writing, if you are going to need some additional consultation you can always appeal to our custom writing service and to receive all the answers you are in need of within the measures of our assignment writing help. Read also: Essay Term Paper on Doing Business in China Creation Paper Cause Effect Papers Analysis Case Studies Term Paper Editing

Saturday, October 19, 2019

Gramscis Notion of Hegemony in Relation to the Youths of Today Essay

Gramscis Notion of Hegemony in Relation to the Youths of Today - Essay Example It should be studied in relation to other matters which could explain more of its attributes and make clear some of its questionable notions. Significantly, an aspect of hegemony could be understood through the study of the behavior and ideology of today’s youth. A particular author has proposed a new concept of hegemony which is relevant to the plight of the present young generation. In exposing the other side of hegemony, Antonio Gramsci has emphasized the importance of making use of one’s intellect in changing the face of the society. In lieu of this fact, the essay will discuss Gramsci’s notion of hegemony and its relation to the youths of today. Gramsci’s Notion of Hegemony Gramsci explains the intellectual aspect of hegemony, suggesting an intellectual struggle instead of power or political struggle. This supports the introductory argument saying that hegemony could actually be understood in light of its other aspects. Intellectual hegemony exists fo r a fact according to Gramsci. He believes that intellectual and cultural activities could also affect social change and not just an economic change (Cuff, et al., 1998). To note, in political economy, hegemony is actually associated to the struggle of economic power in the international arena. To effect an economic change, a particular country applies soft power to influence the economic system of other nations. Certain cultures are used to achieve an economic domination. Nonetheless, for Gramsci, hegemony could actually be viewed in terms of social manipulation. The members of the society could be made to affirm a particular belief or practice through the application of some intellectual activities. Antonio Gramsci actually considers ideas as weapons to change the present state of affairs of the different societies in the world (Cuff, et al., 1998). To note, these ideas are expressed and relayed upon by the influential sectors of the society such as the media. For an idea to have a hegemonic effect, it should be spread to a great number of people. The media is very significant to achieve this objective. It has the ability to influence the thinking of a person by just presenting an idea. It is in this sense that the media could manipulate the thoughts and actions of the members of a particular community. Nonetheless, so as to be in accordance with Gramsci’s notion, the idea which is to be relayed by the media should be one which is aimed at changing the society. What is to be changed is of course the bad image of a particular community. However, for a change to occur there has to be an agent. Relevantly, the youths of today could fill up this need. They could be an effective instrument for social change to happen with the help of the media. In changing the society, there has to be intellectual domination. This means that a certain idea has to be instilled in the people’s mind. The installation however, should be one which could not allow any out side factors to make an opposite claim. In this instance, the members of the society are able to resist any position which is inconsistent to what they have been exposed to. This is to say that for an intellectual domination to take place, the members of the society must learn to adhere to a common idea. The Youths of Today To emphasize, the youths are the ones primarily influenced by the media (Scheibe, n.d. cited in Mazzarella, 2007, p.61). They are the ones who are most exposed to the ideas that the media introduces. Accordingly, the dominant ideology believed in by today’s youth is a product of media’s manipulation. This proves the efficacy of media’s manipulative power. If this attribute is used for the betterment of the society, then the media would be seen as essential in creating the intellectual dom

Friday, October 18, 2019

Instructional Planning and Strategies Essay Example | Topics and Well Written Essays - 1500 words

Instructional Planning and Strategies - Essay Example This type of strategy helps the students to learn more effectively by communicating with each other and do their work with a little fun with their friends. In group assignments students take active participation in the tasks that has been assigned to them. This strategy also encourages the students to teach other students of their group who are little weaker in their studies. (Goleman, D. 1998) Another type of strategy that is been commonly practiced is Collaborative Strategy. This is a type of strategy which is used for broader groups or large groups. This strategy is used for the interactions of larger groups to communicate with each other. In classroom environment this type of strategy is not suitable because in classes the group formation is smaller. This strategy is useful for making school communities, discussion group of faculty and students of school and other broader groups which have much complicated issues to discuss with each other. (Goleman, D. 1998) The Strategy that I have chosen to implement in the classroom is Co-Operative Instructional Strategy. The reason why I chosen the Co-operative strategy rather than collaborative strategy is that it encourages the student to achieve their tasks more efficiently and effectively because this strategy helps the students to achieve the common goals that have been given by the instructor. ... Students in groups also know that there success depends upon team work and every one has to try his/her best to achieve the desired result. It also provides students to learn with more well defined frame work from which they learn from each other in a group. (Johnson, D. & Johnson, R. 1998) The importance of Co-operative Strategy is becoming very fruitful now days. Many teachers are applying this strategy in classrooms to make students feel comfortable and enjoy their studies. Implementing this strategy also improve the self-esteem of students; students who have disabilities for learning also accept this type of learning style and their attitude towards the school eventually becomes good. (Johnson, D. & Johnson, R. 1998) CIRCUMSTANCES FOR IMPLEMENTING THE STRATEGY There are certain conditions that have to be followed for successive results while implementing Co-Operative Strategy. When applying this strategy the teachers must do careful planning and well preparation before going in classrooms. They have to brainstorm their minds that how they will implement the strategy and what would be alternatives regarding this approach if the implementation goes wrong. They should plan and prepare that how they will interact with their students in class and how will they make the environment of classroom more interactive Another condition is the proper formation of groups because if groups are not formed properly then the results of the strategy will not be appropriate. The instructor has to form groups in such a way that every one in the group feels good about their group members and every group has one or two members that are more intelligent then others so that they can teach the group members as well.

Film analysis of Easy Rider Movie Review Example | Topics and Well Written Essays - 1250 words

Film analysis of Easy Rider - Movie Review Example The worth of a spiritual journey is emphasized throughout the movie, something that is closely associated with the idea of freedom in the movie. This is important in the context of an increasingly repressive America in which the movie was set in and released. The space of the carnival is invoked here and this makes one aware of the need for freedom in the everyday lives of men and women. This then becomes an important motif in the movie. This paper shall look at different aspects of the movie and also of its production. It shall do so through an examination of the conditions of its production and the people who were involved in the production of the movie. Dennis Hopper is considered to be one of the first of the directors in Hollywood to have broken from tradition and to imbibe in his methods of filmmaking the rebellious air of the 1960s and 1970s (Dennis Hopper, n.d.). This made him a very popular figure, even though the success of Easy Rider could not be replicated until much late r. The movie in that sense depicts his style of filmmaking and his ideology regarding the process of filmmaking very well. Hopper’s ideas of filmmaking were inspired by the counterculture of the United States of America which was at its heights when the movie was released. The movie remains one of the most important contributions to the development of the agency of the youth of America. After this wave of the counterculture, there was hardly any understanding of the need to revolt for a while in America, something that was recovered in the decades to follow. In terms of the genre of the movie, one may say that Easy Rider falls within the genre of a road movie. A road movie provides certain set patterns of moviemaking to the filmmaker and Hopper abided by this during the making of the movie. The angles that were used during the shots were almost always that which enabled a realistic portrait of the main characters. This involved shots that were taken from a close angle that al lowed the illusion of movement to the audience. This is one of the most important aspects of a road movie. The illusion of movement and pace is provided to the audience which is then gripped with suspense as to the next movement of the characters on screen. The importance of this lies in the fact that the pace of the movie is something that led the audience to identify with it and also to turn it into a cult classic. The fact that Peter Fonda was a part of the cast was a very important step in establishing for the audience the genre of the movie. It also established the nature of the movie as one that was opposed to the hegemonic culture of the times. Fonda had acted in a movie called The Wild Angels in 1966. This was a road movie as well and was a path breaking achievement in its own right (The Easy Rider, n.d.). This opposition to the hegemonic culture earned the movie great success despite the lack of a great deal of technical innovation in the body of the movie as such. The genr e of a road movie was something that was popular even before the release of this movie and it incorporated many of the motifs of the road movie. This included a generous dose of machismo that played a great part even in the final denouement of the movie. The plot, in a great way, is driven by these ideas of machismo that also was a large reason

Holdsworth's English Law Essay Example | Topics and Well Written Essays - 750 words

Holdsworth's English Law - Essay Example In his opinion, Holmes perceives that humans are only obedient to the law because it is what is presented to them by the world and that they obtain results fancied as desirable. While obeying the law, humans tend to ignore the fact that their search for desirable ideas results comes at a high cost those results in bills that are relatively obscure. Holmes’ thought is that even in the present day and age, inventing a different code for humans would result in men who are well off compared to their situations today. However, the worst part is that as of now, humans would be reluctant to adopt codes of life that differ from what they consider to be the norm. Such human attitude could be due to the naivetà © with which principles are eternalized based on social prejudices. Eternalized principles in humans then result in beliefs and want which are reinforced by the laws of imitation. Consequently, until humans are presented with reasons strong enough to change, they remain resistan t and conservative and need no more justification than appetite. Instead of following what they want, the human is expected to and always feel obliged to follow rules since no little doubt makes it inevitable to follow the rule by the courts. In summary, Holmes argues without their conservative nature and internalization of life principles, humans are subject to living a better life that does not bind them to high evitable bills. In my opinion, humans have been subjected to the law since time in memory and from one generation to the other, the law has been internalized as the only means to desirable results. Consequently, humans are reluctant to dare live life without laws or under the guidance of different laws. Humans have grown to remain conservatisms of the law hence always react to change in those laws with great resistance.  Ã‚  

Thursday, October 17, 2019

Internatinal Marketing Strategy Assignment Example | Topics and Well Written Essays - 2750 words

Internatinal Marketing Strategy - Assignment Example Mulberry was established in 1971 specifically to provide fashionable items that would create a formula for its success in the market (Reuters, 2012). Mulberry is a fashionable and luxury brand that people aspire to own. Mulberry is recognized for its wide variety of women leather bags which includes shoulder bags, satchels, totes, clutches, briefcases etc. Due to its classic design and wide variety, it is seen on world’s famous celebrities and models’ arm such as Daisy Lowe, Rosie Huntington-Whiteley and Claudia Schiffer. The company not only provides readymade handbags but also gives its customers a chance to design their own handbags according to their requirements making the English luxury easily accessible. The brand is just not limited for women but also provides handbags and other accessories for men. The collection for men is also eye-catching due to which it is purchased frequently by men. The men’s accessories include wallets, cufflinks, bags, gloves, sc arves and belts (Mulberry, 2012). The company core values remains indistinguishable even after 4 decades which is the main reason for the company’s success. ... Despite the recessionary period the company remains focused on the long-term success and growth (Wood, 2010a). Even after the economic situation the performance of the company was extra-ordinary in 2010 as more than ?40m worth Mulberry’s brand were sold in Britain alone (Wood, 2010b). Global expansion was company’s key success and provided the company with positive news. The international revenues boosted to 61 percent providing high growth opportunities for the company. With the economy in disastrous situation it was important for the company to look for internationalization rather to face economic downturn due to which the sales were expected to fall. The major reason for Mulberry’s internationalization was based on the sharp decline in 2008 for the first time after 2003 which affected the domestic demand for handbags in US and Europe (PRWeb, 2012). The rising demand for international high quality leather handbags in other regions of the world was another reaso n for expanding the business into other geographic regions (Business Wire, 2010). Due to such conditions the best way to hedge against risk was to set foot in such market that was growing influx of foreign brand. One such country includes India where the handbag market is estimated at Rs. 20 billion and projected to grow at an increasing rate of 15 percent annually (Technopak Advisors, 2011). The market for luxury product all over the globe is increasing at a surprising rate and Asia is being targeted as the main market for such products after Europe; due to which India would be the best country to cater (Image 1 and 2). Another advantage to expand in this Asian country will be its low cost in terms of labour and raw material. Figure 1: Worldwide Luxury Goods Market

Academic Report on video game addiction social responsibility Essay

Academic Report on video game addiction social responsibility - Essay Example The authors also believe that the companies which produce the games should be somewhat responsible for their consumers. This particular article would be helpful in establishing distinct ways that society can be more responsible when it comes to this issue as the article presents several specific examples for this. In addition, the article does a good job of presenting an overview of the problem which would be helpful in establishing the background for the paper. Mehroof, Mehwash, and Mark D. Griffiths. "Online Gaming Addiction: The Role of Sensation Seeking, Self-Control, Neuroticism, Aggression, State Anxiety, and Trait Anxiety." CyberPsychology, Behavior & Social Networking 13.3 (2010): 313-316. Academic Search Premier. EBSCO. Web. 26 Oct. 2011. This article provides a study that details some of the consequences in terms of a person’s mental well-being when they have become addicted to video games. For instance, the research illustrates that those who are addicted to video games display an overall increase in aggression, violent behavior, anxiety, and neuroticism. The study found that these behaviors or personality traits were very prevalent in those who were addicted to online gaming. The article would be helpful for a research paper on the topic of video game addiction and social responsibility in that it provides evidence as to how video or online gaming impacts a person negatively. This impact can be pointed to in order to prove that society should be held to a higher standard in terms of how it deals with this type of

Wednesday, October 16, 2019

Holdsworth's English Law Essay Example | Topics and Well Written Essays - 750 words

Holdsworth's English Law - Essay Example In his opinion, Holmes perceives that humans are only obedient to the law because it is what is presented to them by the world and that they obtain results fancied as desirable. While obeying the law, humans tend to ignore the fact that their search for desirable ideas results comes at a high cost those results in bills that are relatively obscure. Holmes’ thought is that even in the present day and age, inventing a different code for humans would result in men who are well off compared to their situations today. However, the worst part is that as of now, humans would be reluctant to adopt codes of life that differ from what they consider to be the norm. Such human attitude could be due to the naivetà © with which principles are eternalized based on social prejudices. Eternalized principles in humans then result in beliefs and want which are reinforced by the laws of imitation. Consequently, until humans are presented with reasons strong enough to change, they remain resistan t and conservative and need no more justification than appetite. Instead of following what they want, the human is expected to and always feel obliged to follow rules since no little doubt makes it inevitable to follow the rule by the courts. In summary, Holmes argues without their conservative nature and internalization of life principles, humans are subject to living a better life that does not bind them to high evitable bills. In my opinion, humans have been subjected to the law since time in memory and from one generation to the other, the law has been internalized as the only means to desirable results. Consequently, humans are reluctant to dare live life without laws or under the guidance of different laws. Humans have grown to remain conservatisms of the law hence always react to change in those laws with great resistance.  Ã‚  

Tuesday, October 15, 2019

Academic Report on video game addiction social responsibility Essay

Academic Report on video game addiction social responsibility - Essay Example The authors also believe that the companies which produce the games should be somewhat responsible for their consumers. This particular article would be helpful in establishing distinct ways that society can be more responsible when it comes to this issue as the article presents several specific examples for this. In addition, the article does a good job of presenting an overview of the problem which would be helpful in establishing the background for the paper. Mehroof, Mehwash, and Mark D. Griffiths. "Online Gaming Addiction: The Role of Sensation Seeking, Self-Control, Neuroticism, Aggression, State Anxiety, and Trait Anxiety." CyberPsychology, Behavior & Social Networking 13.3 (2010): 313-316. Academic Search Premier. EBSCO. Web. 26 Oct. 2011. This article provides a study that details some of the consequences in terms of a person’s mental well-being when they have become addicted to video games. For instance, the research illustrates that those who are addicted to video games display an overall increase in aggression, violent behavior, anxiety, and neuroticism. The study found that these behaviors or personality traits were very prevalent in those who were addicted to online gaming. The article would be helpful for a research paper on the topic of video game addiction and social responsibility in that it provides evidence as to how video or online gaming impacts a person negatively. This impact can be pointed to in order to prove that society should be held to a higher standard in terms of how it deals with this type of

Determination of Density Essay Example for Free

Determination of Density Essay Purpose: To determine the densities of aluminum and zinc cylinders Density is the relationship between the mass of an object and its volume. Sometimes density can be easy to sense. If two objects have exactly the same shape and size, the denser one may feel heavier. If their densities are close together, it can be hard to tell the difference. It gets really tough if you are dealing with materials that have very different sizes or very different shapes. The only way to decide the density of an object is to measure its mass and its volume, then divide. Ex. Density= Mass/Volume Procedure: For Aluminum: 1. Weigh the aluminum cylinders individually on the analytical balance to the nearest 0.0001g and record the weights 2. With a vernier caliper, measure the diameter of each cylinder to the nearest 0.01cm and record 3. Again, using the vernier caliper, measure the length of each cylinder to the nearest 0.01cm and record 4. Compute the volume of each cylinder by using the formula V= (3.14d2h)/4 For Zinc: 1. Weigh the zinc cylinders individually on the top loading balance to the nearest 0.01g, and record the weights 2. Place enough water in a 100mL graduated cylinder to cover the object. Record the volume of water to the nearest 0.1mL by reading the bottom of the meniscus 3. Place the zinc cylinder in the graduated cylinder. Read the new volume and determine the volume for each piece of zinc Data: Density of Zinc Mass#1 104.0168gVolume#1 18mLDensity#1 5.7780g/cm3 Mass#2 92.8178gVolume#2 15mLDensity#2 6.1876g/cm3 Mass#3 72.2115gVolume#3 10mLDensity#3 7.2215g/cm3 Mass#4 55.3077gVolume#4 9mLDensity#4 6.1453g/cm3 Mass#5 35.2653gVolume#5 7mLDensity#5 5.0379g/cm3 Average Density 6.079g/cm3 Density of Aluminum Mass#1 26.48gVolume#1 6.28mLDensity#1 4.22g/cm3 Mass#2 21.50gVolume#2 5.01mLDensity#2 4.30g/cm3 Mass#3 17.58gVolume#3 4.14mLDensity#3 4.25g/cm3 Mass#4 13.10gVolume#4 2.92mLDensity#4 4.48g/cm3 Mass#5 8.68gVolume#5 2.04mLDensity#5 4.25g/cm3 Diameter = 1.025cm Average Density 4.29g/cm3 Conclusions: The densities of both objects were successfully determined. The average density of the aluminum cylinders was 4.29g/cm3, and the density of the zinc cylinders was 6.079g/cm3. Both of these values seem reasonable, and the zinc seems to be slightly heavier than the aluminum. The density of the zinc cylinders was found using the volume by displacement method, and the volume of the aluminum cylinders was found by the formula method V= (3.14d2h)/4. Problems with the equipment may have possibly introduced error into the measurements. The 100mL graduated cylinder used to find the volume of the zinc cylinders was only marked in 10mL increments, requiring estimation for levels in between. The volume of the aluminum cylinders required the use of the vernier caliper to measure the diameter and the length of each cylinder. Improper use of the vernier caliper may have altered the measurements received for the aluminum cylinders. The error introduced by these problems was slight, however, and the calculated densities for both objects are probably quite reliable.

Monday, October 14, 2019

Fe-AZT and Pd-AZT Synthesis and Effects

Fe-AZT and Pd-AZT Synthesis and Effects Synthesis and Effects of Fe-AZT and Pd-AZT on Viability of Human Hepatocytes and Hepatocellular Carcinoma Cells Submitted by: Anna Harutyunyan Introduction Cancer is one of the major causes of mortality in the world. In 2015, according to the National Cancer Institute, over 1.6 million new cases of cancer were reported in the United States. The estimated cancer deaths for the year of 2015 were over 500,000. According to the National Cancer Institute projections, in 2016 an estimated 1.7 million new cases of cancer were diagnosed in the United States and 595,690 people will die from the disease (National Cancer Institute). Although new cancer treatments and therapies are designed and implemented every year, cancer is still the number two cause of mortality in the United States, therefore developing and testing new effective anticancer agents is crucial. Hepatocellular carcinoma (HCC) is one of the deadliest forms of cancers (Venook et al., 2010). The overall 5-year survival rate of HCC is less than 17%, making HCC the fastest rising cause of cancer related death in the United States (American Cancer Society 2016; Mittal and El-Serag, 2013). The annual age-adjusted incidence rates of HCC increased from 1.4 per 100,000 individuals in 1975-77 to 4.8 per 100,000 in 2005-07. An estimated 39,230 new cases of liver cancer (including intrahepatic bile duct cancers) were expected to occur in the US during 2016, approximately three-fourths of which would be hepatocellular carcinoma. An estimated 27,170 liver cancer deaths were expected in 2016 (American Cancer Society 2016). In 80-90% cases HHC occurs with and after cirrhosis. HCCs major risk factors are Hepatitis B and C viruses, cirrhosis, non-alcoholic fatty liver disease (NAFLD), overconsumption of alcohol and exposure to other carcinogenic substances (Mittal and El-Serag, 2013). Liver ca ncer is the sixth most common neoplasm and the third leading cause of cancer-related deaths, accounting for approximately 600,000 deaths annually (Venook et al., 2010). Because of early metastasis and progression, HCCs treatment is difficult, and traditional chemotherapy has shown limited success (Sabokrough et al, 2014). A research study published in 2015 suggested that an organometallic complex of platinum (II) azidothymidine (Pt (II)-AZT) has an antitumor effect on rat hepatocellular carcinoma cells. It was shown that this complex was significantly more effective in tumor suppression than the AZT without platinum (Sabokrough et al., 2014). Several organometallic complexes of AZT (with Zinc, Cobalt, Copper and Iron) were synthesized and characterized previously. The Iron complex of AZT (Fe-AZT) was shown to be the most stable (Shirvastav et al.) and have antimicrobial activity against 4 groups of bacteria. Electron rich ligands like AZT effectively bind and interact with metal ions producing metallodrugs which offer promising therapeutic application in terms of combating the drug-resistant strains of pathogens. It is also logical that a metal ion can influence the biological activity and therapeutic efficacy of the bio-molecule they bind (Shirvastav et al.) Thus it is useful to investigate the effect of a metal ion on the efficacy and mode of action of AZT in suppressing malignant cells and inducing apoptosis. To date, no research has been published regarding synthesis of Pd-AZT the inhibitory effect of both Fe-AZT and Pd-AZT on malignant cells. The aim of this research project is to synthesize Fe-AZT and Pd-AZT, confirm their structure and molecular mass and test their effects on viability of human hepatocellular carcinoma cells and normal human hepatocytes. Background Normal cell cycle In order to understand the biology of cancer it is crucial to understand the cell cycle of normal cells and cancerous cells. All cells in a given organism are under strict control of multiple regulatory agents, such as RB or p53 that control cell growth and keep the proliferative index stable. If there is a need for the cell to divide, the proliferative genes will turn on, or the suppressor genes that keep proliferation from occurring will be shut down, which will result in cell division (Hardin et al., 2014). The normal cell cycle consists of the following phases: G1, S, G2, M. During the G1 phase duplication of organelles, membrane systems and other important components happens. There is an important checkpoint at the end of this phase referred to as the restriction checkpoint, which verifies that DNA synthesis was successful and no errors have been detected. Next is the S phase during which the cell duplicates each chromosome. During the G2 the rest of the components that were not synthesized in the G1 phase are synthesized. A checkpoint after this phase makes sure the cell is ready to divide, and no errors in chromosome duplication were made. Mitosis is the next phase, when the cell physically divides (cytokinesis) making two identical daughter cells. A checkpoint during this phase checks if both of the daughter cells received the correct number of chromosomes. After division, the cell may remain in its silent G0 phase, when it does not divide, but continues to function. If any errors are detected on any of the checkpoints, the cell cycle is put on hold and the cell will undergo apoptosis. This process is governed my many enzymes and complexes, and theoretically, malfunction of any of these enzymes may result in uncontrolled cell division/proliferation. This can be the onset of carcinogenesis. Figure 1. The cell cycle phases with their checkpoints. Cancer cell cycle It is important to note that the normal cell cycle is under control of thousands of regulatory elements that are coded for by different genes. If mutations occur in the genes that code for the key elements keeping cell proliferation at bay, one level of control over the cell cycle is lost. There are cell signaling mechanisms through which immune cells detect faulty cells, send them death signals and the faulty cell undergoes apoptosis. It takes more than one mutation for a normal cell to start behaving like a cancer cell. Usually it is either the loss of the function of suppressor genes, or overexpression of proliferative genes that result in uncontrolled cell proliferation. When the cell becomes malignant, it loses the ability to respond to death signals, thus does not undergo apoptosis. The malignant cell cycle is slower than the normal cell cycle, however, since the cancer cells keep dividing and do not die, their number grows exponentially resulting in tumors (Weinberg, 2014). There is distinct cytological difference between normal and cancer cells (Figure 2). A normal cell has a smaller, regularly shaped nucleus, a low nucleus/cytoplasm ratio, is well differentiated and has well defined borders. Cancer cells have larger, irregularly shaped nucleus, high nucleus/cy toplasm ratio, are less differentiated and have irregular borders. In contract with normal cells that adhere to each other, cancer cells are less adhesive and break away from each other (Weinberg, 2014). Figure 2. The comparison of the cytology of normal cells and cancer cells. Azidothymidine (AZT), Fe(III)AZT, Pd(II)AZT Azidothymidine (AZT, Zidovudine) is a thymidine derivative in which the 3-hydroxy group is replaced by an azido group (Figure 3). It has been shown to have antitumor effects on different animal carcinoma cells both in vitro and in vivo through inhibition of telomerase activity and by causing cell cycle arrest (Gomez et al., 2012; Hadizadeh et al., 2014, Cooper and Lovett, 2011; Matteucci et al., 2015). Figure 3. Thymidine (left), Azidothymidine (right). Since cancer cells have higher proliferation rate than normal cells, their thymidine turnover rate is higher, which could contribute to their increased sensitivity to AZT. Several studies conducted by Fang et al., have shown that a hepatocellular carcinoma cell line (HepG2) is significantly more sensitive to AZT toxicity as compared to the normal hepatocyte (THLE2) sensitivity (Fang et al., 2014; Fang and Beland, 2009). The current hypothesis on how AZT affects the cell suggests that AZT is phosphorylated intracellularly yielding AZT-triphosphate and AZT-monophosphate. The AZT-monophosphate can be incorporated into the DNA structure instead of thymidine due to its similar molecular structure and shape. However, in contrast with thymidine, AZT lacks the 3 hydroxyl group which is the group that forms phosphodiester bonds between nucleotides in the DNA backbone structure. This means, wherever the AZT phosphate is incorporated in one of the DNA strands during DNA replication, the elongat ion of that strand halts (Figure 4). This is one of the mechanisms through which AZT causes damage to DNA (Fang et al, 2014). The commercial name of AZT is Zidovudine, and it is the basis of AIDS treatments. AZT blocks the replication of HIV-1 virus by competitively inhibiting the viral reverse transcriptase (RT). In other words, HIV RT prefers AZT to normal nucleotides. As described above, AZT is phosphorylated to AZT-triphosphate and is incorporated into viral DNA, halting nucleotide chain elongation. It is also known that AZT-triphosphate can be incorporated into eukaryotic DNA, although its affinity for DNA polymerases is lower than that for RT (Gomez et al, 2012). It was shown that Pt(II)-AZT is more effective in suppressing cancer cells than AZT, thus it has been suggested that having a transition metal bound to the central nitrogen atom of the azido group increases the complexs affinity for G-C and A-T base pairs and the P-backbone of DNA (Das and Pitre, 2007; Sabokrouh et al, 2015). Materials and Methods Fe-AZT and Pd-AZT synthesis To carry out the synthesis of Pd and Fe complexes, solid AZT and a standard ion solution of each metal (iron nitrate nonahydrate (Fe(NO3)3 ·9H2O and palladium chloride (PdCl2)) will be purchased from Sigma Aldrich (St. Louis, MO). Synthesis will be performed according to the protocol by Das and Pitre (2007). A 1:1 molar ratio of aqueous solution of AZT and metal ion will be refluxed for 3 hours. The volume of the reaction mixture will be reduced by 75% in order for the complex to precipitate. The solid product will be vacuum filtered, washed twice with ice-cold water, recrystallized and air-dried overnight. Infrared absorbance spectra will recorded for the AZT, Fe-AZT and Pd-AZT complexes. In the experiment conducted by Das and Pitre (2007) the comparison of IR spectra of pure AZT and its complex with Fe, the spectrum indicated a shift in bands from 2170 to 2150 cm-1 due to complexation through N atom of azido group. A similar band shift in the IR spectrum of Fe-AZT and Pd-AZT is expected. A Matrix Assisted Laser Ioniation/Distortion Time-of-Flight (MALDI TOF) mass spectrometry analysis will be performed for the Fe-AZT and Pd-AZT to determine the molar mass and the stoichiometry of the complexes. The matrix for analysis will be composed of 1:1 saturated Anthranilic Acid and Nicotinic Acid (Sigma Aldrich, St. Louis, MO). The samples and matrix will be dissolved in 45% acetonitrile: 55% water (van Kampen et al., 2004). Cell cultures HepG2, THLE2. Liver carcinoma cell line HepG2 and normal human liver cell line THLE2 will be obtained from American Type Culture Collection (Manassas, VA). The standard protocol recommended by ATCC will be used for establishing and maintaining hepatic cell lines. The cell lines will be plated at a density of 5 x 103 cells/cm2. HepG2 cells will be cultured in DMEM with 10% fetal bovine serum and antibiotics (penn/strep). THLE2 cells will be cultured in LHC-8 medium with 70ng/ml phosphoethanolamine, 5ng/ml epidermal growth factor, 10% fetal bovine serum and antibiotics (Fang et al., 2009). After ensuring sufficient cell growth and several passages of each cell line, the two cell lines will be divided into 4 groups each: control (no treatment) and treated with each drug: AZT, Fe-AZT and Pd-AZT (Table 1). Table 1. The experimental setup of the control and experimental groups of cells. Control 1 (C1) THLE2 cell line (no treatment) Control 2 (C2) HepG2 cell line (no treatment) Experimental 1 (E1) THLE2 cell line+AZT Experimental 2 (E2) HepG2 cell line+AZT Experimental 3 (E3) THLE2 cell line+Fe-AZT Experimental 4 (E4) HepG2 cell line+Fe-AZT Experimental 5 (E5) THLE2 cell line+Pd-AZT Experimental 6 (E6) HepG2 cell line+Pd-AZT The cells in the treated groups will be further categorized by the concentrations of the drug. HepG2 cells will be incubated with 2, 20 or 100  µM aqueous solution of AZT, Fe-AZT or Pd-AZT for 14 days. THLE2 cells will be incubated with 50, 500 or 2500  µM aqueous solution of AZT, Fe-AZT or Pd-AZT for 14 days. Each group of cells will be seeded at 5 x 103 cells/cm2 density in 6-well plates. The cells will be passaged weekly during the two-week treatment period. The dosage and incubation time were chosen based on a similar study (Fang et al., 2013; Matteucci et al., 2015; Sabokrouh et al., 2015). Cell viability assay After 14-day treatment period, 103 106 cells from each group will be seeded in a 96-well plate, incubated for 4 hours, and treated with MTT reagent, followed by a 8-12 hours incubation at 37 °C. After the incubation with MTT, when the cells have metabolized the yellow tetrazolium dye (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) to purple formazan, the cells will be treated by a detergent to release the formazan into the solution, and the absorbance will be measured at 570nm using an ELIZA reader. The number of metabolically active cells will be determined using a previously made calibration curve. The statistical differences will be calculated using a Two-Way ANOVA and Tukeys Post-Hoc Test. Anticipated outcomes. The expected mass-to-charge ratio from mass spectrometry analysis of Fe-AZT complex is 323.1, that of Pd-AZT is 373.6. Based on the published literature and the adopted hypothesis, all three drugs are expected to decrease cell viability. The concentration of either drug should have positive correlation with decrease in cell viability. Based on previous observations, it is expected that the HepG2 cells will be significantly more sensitive to both complexes, thus will be significantly less viable after the treatment compared to the THLE-2 cells. Study Participants and Timeline Anna Harutyunyan is the primary author of this study. She is currently a senior biology and chemistry major at Wilson College. This project will serve as Annas senior research project. She will conduct the research and present the results with the supervision of her advisors Dr. Deborah S. Austin (Sponsoring PAS member) and Dr. M. Dana Harriger (PAS Member). The research study began in September 2016 and will be completed by April 2017. Annas research findings will be analyzed and written as her senior thesis. Anna will also present her findings at the 2017 Pennsylvania Academy of Science meeting and at the Wilson College research colloquium. Budget Item Price MTT Assay Kit (ThermoFisher) $235.00 Zidovudine (Sigma) $124.00 LHC-8 medium (Gibco) $140.00 Total $499.00 Facilities and Equipment The MALDI TOF mass spectrophotometer will be provided by Pennsylvania State College of Medicine Mass Spectrometry Facility under supervision of Bruce Stanley, PhD. All materials, other instruments, and equipment not listed, including cell culture media and supplies, will be provided by the Department of Physical and Life Science of Wilson College. References       American Cancer Society. Cancer Facts Figures 2016. Atlanta: American Cancer Society; 2016. Bilsland AE, Stevenson K, Liu Y, Hoare S, Cairney CJ, Roffey J, et al. (2014) Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms. PLoS Comput Biol 10(2): e1003448. doi:10.1371/journal.pcbi.1003448 BIOL2060 Cell Cycle [Photograph found in Department of Biology Memorial University of Newfoundland]. (2015). In Hardin Bertoni (Authors). Retrieved March 30, 2016, from http://www.mun.ca/biology/desmid/brian/BIOL2060/BIOL2060-19/CB19.html Chen, Yi-Bin. Liver Cancer Hepatocellular Carcinoma: MedlinePlus Medical Encyclopedia. U.S National Library of Medicine. U.S. National Library of Medicine, 1 Aug. 2015. Web. 10 Apr. 2016. Cooper, D. L., Lovett, S. T. (2011). Toxicity and tolerance mechanisms for azidothymidine, a replication gap-promoting agent, in Escherichia coli. DNA Repair, 10(3), 260-270. http://doi.org/10.1016/j.dnarep.2010.11.007 Das, R., Pitre, K. S. (september 2007). Bioinorganic studies on Fe (II)- zidovudine (azt) complex. Indian Journal of Chemical Technology, 14, 526-528. Retrieved February 20, 2016. Fang, J.-L., Beland, F. A. (2009). Long-Term Exposure to Zidovudine Delays Cell Cycle Progression, Induces Apoptosis, and Decreases Telomerase Activity in Human Hepatocytes. Toxicological Sciences, 111(1), 120-130. http://doi.org/10.1093/toxsci/kfp136 Fang, J., Han, T., Wu, Q., Beland, F., Chang, C., Guo, L., Fuscoe, J. (2014). Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine. Archives Of Toxicology, 88(3), 609-623. doi:10.1007/s00204-013-1169-3 Gomez, D. E., Armando, R. G., Alonso, D. F. (2012). AZT as a telomerase inhibitor. Frontiers in Oncology, 2, 113th ser. Retrieved March 11, 2016, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434370/ Hadizadeh, S., Najafzadeh, N., Mazani, M., Amani, M., Mansouri-Torshizi, H., Niapour, A. (2014). Cytotoxic Effects of Newly Synthesized Palladium(II) Complexes of Diethyldithiocarbamate on Gastrointestinal Cancer Cell Lines. Biochemistry Research International, 1-9.doi:10.1155/2014/813457 Hardin, J., Bertoni, G., Kleinsmith, L. J., Becker, W. M. (2014). Beckers world of the cell (8th ed.). Boston: Benjamin Cummings. Harrington, J. A., Reardon, J. E., Spector, T. (1993). 3-azido-3-deoxythymidine (AZT) monophosphate: an inhibitor of exonucleolytic repair of AZT-terminated DNA. Antimicrobial Agents and Chemotherapy, 37(4), 918-920. van Kampen Jeroen J.A., Fraaij Pieter L.A., Vishal Hira, van Rossum Annemarie M.C., Hartwig, Nico G., de Groot Ronald, Luider Theo M.. A new method for analysis of AZT- triphosphate and nucleotide-triphosphates. Biochemical and Biophysical Research Communications, Volume 316, Issue 3, 9 April 2004, 151-159] Matteucci, C., Minutolo, A., Marino-Merlo, F., Grelli, S., Frezza, C., Mastino, A., Macchi, B. (2015). Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB. Life Sciences, 127, 90-97. doi:10.1016/j.lfs.2015.01.038 Mittal, S., El-Serag, H. B. (2013). Epidemiology of HCC: Consider the Population. Journal ofClinical Gastroenterology, 47(0), S2-S6.http://doi.org/10.1097/MCG.0b013e3182872f29 National Cancer Institute. (n.d.). Surveillance, Epidemiology, and End Results Program. Retrieved February 16, 2016, from http://seer.cancer.gov/statfacts/html/all.html Neto, V. (2013, January). AZT action [Photograph found in Organic Chemistry]. Retrieved April 1, 2016, from http://wwwblogvine.blogspot.com/2013/01/azt-was-originally-intendedto- treat.html (Originally photographed 2013, January 20) Normal And Cancer Cells Structure [Photograph found in Cells or Tissue Abnormal Cells or Tissue Cells or Tissue Normal Cells or Tissue Historical Graphics, National Cancer Institute]. (2001, January 1). In P. Kenny (Illustrator). Retrieved April 1, 2016, from https://visualsonline.cancer.gov/details.cfm?imageid=2512 (Originally illustrated 1990, April) Pichard, L., Raulet, E., Fabre, G., Ferrini, J. B., Ourlin, J. C., Maurel, P. (2006, February). Human hepatocyte culture. Retrieved March 11, 2016, from https://www.researchgate.net/publication/7063976_Human_hepatocyte_culture Sabokrouh, A., Vaisi-Raygani, A., Goodarzi, M. T., Khatami, S., Taghizadeh-jahed, M., Shahabadi, N., à ¢Ã¢â€š ¬Ã‚ ¦ Shakiba, Y. (2015). Comparison between Platinum-Azidothymidine and Azidothymidine Effects on Bcl-2 and Telomerase Gene Expression in Rats with Hepatocellular Carcinoma. Avicenna Journal of Medical Biotechnology, 7(2), 50-56. Sabokrouh, A., Goodarzi, M. T., Vaisi-Raygani, A., Khatami, S., Taghizadeh-Jahed, M. (2014). Effects of Treatment with Platinum Azidothymidine and Azidothymidine on Telomerase Activity and Bcl-2 Concentration in Hepatocellular Carcinoma-Induced Rats. Avicenna Journal Of Medical Biotechnology, 6(4), 200-209. Telomere Shortening Determines the Proliferative Lifespan of Human Diploid Fibroblasts. 2001. Nature Reviews. By Nicole F. Mathon and Alison C. Lloyd. Web. 21 Mar. 2016. ThermoFisher Scientific. (n.d.). MRNA Extraction. Retrieved March 11, 2016, from https://www.thermofisher.com/us/en/home/life-science/dna-rna-purification-analysis/rna- extraction/rna-types/mrna-extraction.html Venook, A. P., Papandreou, C., Furuse, J., De Guevara, L. L. (2010). The Incidence and Epidemiology of Hepatocellular Carcinoma: A Global and Regional Persprective. The Oncologist, 4(15), 5-13. Retrieved March 11, 2016, from http://theoncologist.alphamedpress.org/content/15/suppl_4/5.long Weinberg, Robert A. The Biology of Cancer. 2nd ed. New York, NY: Garland Science, 2014. Print.

Sunday, October 13, 2019

Essay --

The Triangle of Death, The Limbo of the Lost, The Twilight Zone, The Port of Missing Ships, The Devil’s Triangle, The Hoodoo Sea, The Deadly Triangle. These and many more are names for the mysterious Bermuda Triangle. The Bermuda Triangle has been a huge mystery to many since the early 1900's. The Triangle is an area located in the western Atlantic Ocean, where supposedly many ships, people, planes, and other objects disappear unexplainably. The three points of location that connect the triangle are Miami, Florida, Bermuda, and San Juan, Puerto Rico. The triangle covers about five hundred thousand square miles of ocean. However, there is no official boundaries or markers for the triangle, just recognized linings. Over the past five centuries, more than a thousand ships and planes have disappeared inside of the triangle boundaries, and still to this day continue to do so. There are many theories behind these happenings. However, no one has yet found the real truth behind it. One of the most famous, or well-known happenings of the Bermuda Triangle is the disappearance of Flight 19. This happened in December, 1945 during a US Navy training exercise. Fourteen crew members on a route mission disappeared after sending out many radio messages, and when two Martin Mariner rescue planes came to search for them, only one came back while the other strangely could not be found. It is still not fully known what went wrong here. Many wrecked parts from Flight 19 have never been recovered. More famous incidents of the Bermuda Triangle are: The USS Cyclops and three hundred and nine crew members went missing in 1918, the Douglas DC-3 plane with thirty-two people that went missing in 1958 (no trace of aircraft was ever found), and a yacht that was... ...iangle disappearance is no more logical than trying to find a common cause for every automobile accident in Arizona.† Neither maritime insurance leader Lloyd’s of London, or the U.S. Coast Guard, do not see the Bermuda Triangle as an especially dangerous place. They say, â€Å"In a review of many aircraft and vessel losses in the area over the years, there has been nothing discovered that would indicate that casualties were the result of anything other than physical causes. No extraordinary factors have ever been identified.† So it is ultimately up to you to decide what you believe in when it comes to the Bermuda triangle. While it has become very popular to link the Bermuda Triangle to paranormal activity, most investigations claim they happen from bad weather and human error. With all the hundreds of theories, still today, the mystery of the Bermuda Triangle remains.

Saturday, October 12, 2019

Hitlers Rise To Power :: essays research papers

  Ã‚  Ã‚  Ã‚  Ã‚  As most people on this planet know, World War II has been over for more than 50 years. The ideals of Hitler, a man wanting to eliminate all Jews and minorities, are views that can be questioned. Most people have difficulties accepting failure, and when failure arises people look elsewhere to blame someone else for their shortcomings. In society these people are called scapegoats. The question that comes to mind is Who was Hitler and what were his thoughts?   Ã‚  Ã‚  Ã‚  Ã‚  Most prominent leaders that can be thought of as great dictators were extremely forceful. Julius Caesar and Napoleon both rose up during troubling times of their country. They did this by going to war and winning, they would take over a country, set up a government, and then move on. Hitler was the exact opposite, he was a barbarian who ruled by striking fear into people. â€Å"They regard me as an uneducated barbarian. Yes, we are barbarians! We want to be barbarians! It is an honorable title.† (Rauschning, Hermann. The Voice of Destruction New York, 1940, p.80) The government that Hitler proposed had no real law. The people were to follow what they were told by those who were ranked above them, thus always leading back to Hitler. Hitler taught children to spy on their parents, and then report their wrong doings. He wanted people to hate their neighbors. He wanted those people of different, and for that matter â€Å"wrong† religions, political party, and/or race to be eliminated. A lot of the time when people look at history books and see a leader such as Hitler they might think that it was a long time ago, or that people were not that smart. Hitler rose to power in a time when people were literate, a majority of people were fairly smart, and none the less it was a mere 50 years ago.   Ã‚  Ã‚  Ã‚  Ã‚  As most people across the globe will agree Hitler had unsightly political views. He preached that before a government can reach a victory or a happy state it must first undergo a change. This is why the nazi movement was necessary. Hitler preached propaganda, the information that today would be found in The National Enquire. What he preached was what people wanted to hear, it was an easy route out of all of their troubles. He was able to relay his message across the people in Germany and draw more than a third of a vote in a free contested election.

Friday, October 11, 2019

Make and Recieve Telephone Calls

The telephone that I use for work is a complicated phone and I don’t use all of its features, the basic features it has are the function to answer the phone and transfer calls to another person, it also allows me to answer a call from some else’s phone that is in my group. To transfer calls to another colleague I have to press R on the phone and then enter my colleague extension number for the call to be transferred. If I wanted to answer another colleagues phone I simple have to press *84 on the keypad and pick up the phone to receive their call.I am able to adjust the volume of the ring and I am able to place the call on loud speaker. I am also able to turn on or off the microphone in the handset as well as view the list of the numbers that I called last. I am also able to create a directory of number on the phone to be able to make calls quickly, on top of this there are 12 preset phone numbers with quick dial buttons on the phone however the previous owner had set t hese up and I am unable to change them.The phone is also capable of diverting the call to another phone and send messages between phones although I haven’t used this yet. Before making a phone call it’s a good idea to identify the purpose of the call as it would make me the caller sound more professional as I know exactly what I want and would waste no time with anything else, it would also allow me to have information that I can then use to prepare questions to ask and get the necessary details which I may require.An example of this is when a colleague requested that I acquire some information regarding the prospectus of the local colleges I had to identify whom I was going to make the call to and what the call would be regarding, after speaking to my colleague more and gaining the knowledge of exactly what they wanted me to get I was able to identify that the purpose of this call was to contact the college and ask what lessons they would be providing that relate to t he request made by my colleague.There are multiple ways to acquire the telephone number of people in my organisation as I can use the local address book to get there details, for example if I only knew there phone number which within the organisation would only be their extension number, I could use that to acquire their name and location as well as the department they work in, and I could do the same with only their name. Another method of gathering the contact details of someone is either using the internet to look up their business and get the information from their or ask a colleague if these have access or know the individuals name or number.I was request to book a venue for a stakeholder workshop for a colleague and they provided me with the specifics of the workshop but not where the workshop would be, they left that up to me to decide, therefore I had to determine which venue would best suit the requirements made. I spoke to another colleague that recommended Dillington Hous e, however they were unable to provide any contact details for me. Due to Dillington House not being within the organisation I was unable to use the local address book so I had to use the internet to acquire their contact numbers.After locating their website via a Google search I found the contact details for a Robin Kyd who arranged bookings. To finally make the call to the individual within the organisation I would simple enter their extension number on my phone and the call would be put through. On the other hand if I need the contact details of someone outside the organisation I would either have to research their details on the internet, this would include looking up their business, and getting their number from their website.However this number may only be a general enquiry number and I would then contact them and ask for the relevant details I need. However to make the phone call to someone outside the organisation I simply have to enter the number 9 before entering their ful l phone number to make the call. An example of me doing this is when I had to make a phone call to Dennis Quick who works for Taunton Deane, I was given his contact details from a colleague when they passed a message along to me.When I first made the call the line was engaged and I couldn’t get through, but when I rang again later that day I reached Dennis’s secretary who said he was available and transferred my call along to him, it was confirmed that I was speaking to the correct person when he introduced himself as Dennis Quick. The purpose of giving a positive image of myself and my organisation is to give me a polite, efficient and professional image otherwise people will not respect or take you seriously and if you have a professional image then this reflects well on the organisation.If you have a positive image then communication between people both within and outside the organisation would be better and more efficient possibly allowing for the transfer of infor mation quicker and efficiently. Summarising a telephone conversation before the call ends can be beneficial to both parties as it allows everyone to agree on what has been said and ensure there are no confusions this is especially useful when the telephone conversation has been going on for a long period of time and various things have been discussed, its easy to lose focus on what has previously been said and summarising overcomes this.It also allows objectives to be clear and information fresh in the mind for both parties to write down or relay to another person or persons. An example of this is when I had to make alterations to a booking that I had made with a business called Monks Yard in Ilminster. After discussing with the person that was arranging the meeting on their end, I ended the telephone conversation by asking the person to repeat the amendments that I wanted them to make and once I was happy that he had everything correct by checking with the list that I had in front of me at the time, I thanked them and ended the call.When a call comes into the office I’ll always take a name (full if possible and preferably) and the company they are calling from, I’ll try and obtain from the caller either what the problem is exactly or from which department the problem arisen from and if they know who within the department they spoke to. I’ll pass messages along to departments or relevant staff members and see what information can be found to resolve the problem.If this is not possible try and locate a member of staff who can help from the information obtained from the caller e. g. A company was expecting a Goods Receipt Note via SAP a week ago, I logged into SAP and saw that I needed to send the Goods Receipt Note but as I didn’t have an training and didn’t know what to do, I located a staff member who I knew had training on this and could help me, I contacted her department and was put through to her and she talked me throug h the problem, however I hadn’t been set up correctly and couldn’tsend out a Good Receipt Note and had to contact IT and get it fixed, during this entire period of getting it fixed and finally sending out the GRN I kept the company informed on what happened and gave them an estimated time that they would receive the GRN. The organisational structure of County Hall is that of a hierarchical structure which uses clear reporting lines and it is easy to see what each team is called and how many people are in that team and how they relate to other people in the system.The communication channels for us are different per team or department for me my phone is linked with everyone else’s in my team and I am able to answer their phone by entering *84 however I am not able to answer any other phone on the floor this way. I can contact anyone internally as long as I know their extension number as this is the main method of contacting anyone internally and I can call anyone externally by simply entering the number 9 before entering their phone number.When I make a external call I introduce myself by saying my name and company that I’m calling from, if I know prior to the phone call which member of staff or department that I want to call I would request to speak to them. If I don’t know who I’m reaching I would explain why I’m calling and request help on locating the member of staff that can help me. When I’m connected to this person, I ideally should have some questions ready or know exactly what information I require.At the end of the call I should summarise the call and recap information to make sure that it is accurate. If a fault was to occur with my telephone I would simply call the IT department and inform them when the problem occurred and how frequent it is happening, they would resolve the issue by either providing a replacement handset until it is fixed or locating the fault and fixing it at their earliest c onvenience.When I received a call I should identify who the caller is and their needs to do this I should follow my phone call procedures and gather the callers name and who they calling from, with this done I have now identified my caller and go about identifying their needs. Sometimes the caller will not provide you with their name at the start of the call as for example in a telephone conversation I had with a man asking for a colleague who was away from the desk, after following call procedures I asked to take a message, once the caller had given me his message, I asked who the call was from and he provided me with his name.Following procedures I will then ask the caller what I can help them with and they should briefly explain why they are calling, depending on why they have called and what my job entails I will either transfer them to another member of my team who can deal with their call, check the availability of a team member and inform the caller that they will call them b ack at a certain time or providing the information that they require to the best of my ability, although I will inform them that I am new and may not be able to answer all their questions.An example of this is when I received a phone call from a lady who wanted to submit a complaint to our department, after taking her name and contact details, she proceeded to tell me why she was complaining and what she would like done about it.During this telephone call I was taking notes so I could pass along her message when the call had ended, at the end of the call when she had finished explaining the problem, I repeated to her the points that I had taken and asked if these were correct, after making some small arrangements I summarised the information that she had given me and once she confirmed it was all correct, I informed her that I was going to pass this along to the relevant person and he would respond as soon as he can, I also informed her that I would call her when I had done this so she would know that action had been taken and it would also create a positive image of myself and my team. Giving accurate information to callers means when someone calls they have done so with the anticipation of getting their question or query answered promptly and professionally. Having up to date information available in a clear and concise manner will confirm in the callers mind that they question has been answered properly. For example if someone rang up asking for details on the most recent consultation regarding one of the teams projects and I gave them a out of date or incorrect document details then it would make a bad impression for the team and could affect their reputation as they may be deemed unreliable.From a callers point of view they want their personal details kept secure and confidential by showing this when dealing with a caller I am showing them that I can be trusted with their personal information and from my point of view, I need to keep the information priva te and respect their privacy otherwise I could become liable for prosecution under the Data Protection Act and with the information that my team handles a lot of it is private and confidential so this is a daily thing. If any confidential or information to do with security is given out, then it is causing a threat to others. Types of information that could affect confidentiality and security are people’s personal details so in my case it would be personal phone numbers and addresses. Therefore to reduce the risk of breaking confidentiality the information should only be handled by those that absolutely need access to it and if anyone requests the information then I should ask the persons whose information it is if they can have it or inform the person asking that someone will contact them.The Data Protection Act was setup to prevent confidential and security information from being given out and it is breaking the law if I was to do so. All these sorts of information should be handled by a maximum of 2 people and seen by no one else; this way no information will be revealed. After answering the call following the team’s procedure, I’d ask the caller if they know the name of the person they wish to speak to, if they don’t ask regarding which department. If they caller doesn’t know who to speak to then I would find out briefly, as they call may be regarding a private matter, what the call in about. Using the information I had gathered it would make it easier to transfer the call to the right person or department.If the person the caller is trying to reach is unavailable either because they are out of the office or away for the moment, then I would try to located someone else that may be able to take the call and explain to them the name of the caller, and what they are calling about as this would save time for the caller as they wouldn’t have to relay the information again. A lot of the time the case with transferring a c all is that the caller would either leave a message or inform me that they would call later, however with some calls that I receive the person they are trying to reach have left the desk momentarily and return while I’m still talking to the caller allowing me to transfer the caller to the person they were trying to reach. I would then inform the caller that I am transferring them to that particular person and explain why they would be more useful and helpful to deal with their request.Another option would be to leave a message I would either leave a message on their answering machine or a note on their computer, I would leave the following details; who the caller was, full name, where they were calling from, the time that they rang and the details of the call and any specific details or requests the caller wanted the intended receiver to know. A problem that could occur and has occurred it when transferring a call to a colleague the connection to the caller has become lost du ring the transfer, To amend this I would simply call them back apologising for the inconvenience, also ringing them back would show that I am keen to help them and am trying my best to provide good customer service. I would then log the problem as a technical fault, however if the problem kept occurring then I would report the problem with the IT department.Another problem that could occur is that I may transfer the caller to the wrong person this may have happened due to a system fault or a technical fault, though in my case it could be due to the fact that I’m new and could have made a mistake. If the caller went to the wrong number then the call would circulate around back to me and I would deal with the call accordingly. However if a call had been transferred to me by mistake then I would explain to the caller that unfortunately they had been transferred to the wrong person, though not necessarily the wrong department. I would apologise to the caller and ask for them to e xplain the problem and then transfer them to the correct person.I would then take a note of the problem and if the problem continued I would contact the transferee informing them that they have transferred the call to the wrong person and if it persists then I would inform IT about the problem. When receiving a phone call from an individual I would follow my teams phone call procedures this would involve doing the following things. If it was my phone that was ringing I was answer it as promptly as possible with the greeting, â€Å"Isaac Young, Major Programmes†, If it was another member of my teams phone that was ringing and due to the layout of the office it is hard to tell which phone is ringing, It is procedure to wait for the phone to ring three times and if it hasn’t been answered by then, I would enter *84 on the phone to take the call and answer with the previous greeting.Once I am connected to the caller I would obtain who the caller is and where they are from, by now the caller has usually mentioned the person they wish to speak to, if the caller mentions why they are calling this is noted when transferring the call and it is not company procedure although it is recommended that you ask what the call is in reference to. When reporting a fault to the IT department I have to be as exact as possible as this will help the issue to be resolved as fast as possible. Having an accurate account of when the problem first started and the frequency the fault occurred, what is actually happening, which can be obtained by the fault log that I have written down. I would request IT to provide a replacement phone while the problem is amended.